• Detection of Arc/Arg3.1 oligomers in rat brain: constitutive and synaptic activity-evoked dimer expression in vivo 

      Mergiya, Tadiwos Feyissa; Gundersen, Jens Edvard Trygstad; Kanhema, Tambudzai; Brighter, Grant Mitchell; Ishizuka, Yuta; Bramham, Clive Raymond Evjen (Journal article; Peer reviewed, 2023)
      The immediate early gene product activity-regulated cytoskeleton-associated protein (Arc or Arg3.1) is a major regulator of long-term synaptic plasticity with critical roles in postnatal cortical development and memory ...
    • Development and Validation of Arc Nanobodies: New Tools for Probing Arc Dynamics and Function 

      Ishizuka, Yuta; Mergiya, Tadiwos Feyissa; Baldinotti, Rodolfo Da Silva Mazzarini; Xu, Ju; Hallin, Erik Ingmar; Markusson, Sigurbjörn; Kursula, Petri; Bramham, Clive Raymond Evjen (Journal article; Peer reviewed, 2022)
      Activity-regulated cytoskeleton-associated (Arc) protein plays key roles in long-term synaptic plasticity, memory, and cognitive flexibility. However, an integral understanding of Arc mechanisms is lacking. Arc is proposed ...